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How Chronic Non-Joint Pain is Helped by Prolotherapy 
K. Dean Reeves, M.D.

Chronic pain is very often from strain (tendon damage) or sprain (ligament damage) 
which can occur for injuries or just overuse. This is because many nerve endings are present in tendons and ligaments and when stretched due to weakness in the structure, they will cause pain.  The patient feels tight as muscles try to protect the area but the problem is loose or weak connective tissue.  Normal repair takes 6-8 weeks and is often incomplete.  Normal repair attempts to thicken and tighten the weak and loose tendon/ligament and requires growth factor elevation.   If the tendon or ligament does not get tight or strong enough, the muscles stay chronically tight causing stiffness and the nerves continue to be stimulated causing pain with movement or at rest. 

Growth factor elevation is only increased for several weeks after injury. Injection to raise growth factor levels causes  the repair cycle to be repeated, allowing the tendon or ligament to get stronger and then decrease or eliminate symptoms.   Indications of damage to tendons/ligaments can include  referred symptoms such as pain, numbness, or coldness, symptoms of looseness such as clicking, popping, or feeling out of place or loose and secondary changes in muscle such as  weakness, tightness, or twitches seen in muscle with stimulation of the weak/irritable area in the tendon/ligament. (Twitch contractions.) 
 

Introduction to Prolotherapy
Why Get Prolotherapy? Donna Alderman, D.O.
What is Prolotherapy? Alvin Stein, M.D.
Introduction to Prolotherapy Ross Hauser, M.D.
How Safe Is Prolotherapy? Ross Hauser, M.D.
The Importance of an Experienced Prolotherapist Ross Hauser, M.D.

Non-Surgical Tendon, Ligament and Joint Reconstruction William J. Faber, D.O.
How Does Prolotherapy Work? Marc Darrow, M.D.
When Prolotherapy May Not Work David Harris, M.D.  
Twenty Common Questions About Prolotherapy
David Harris, M.D.
The History of Prolotherapy Ross Hauser, M.D.

Curing Chronic Pain with Prolotherapy Scott Greenberg, M.D.
Why So Many Turn To Prolotherapy David Harris, M.D.
Prolotherapy and Chronic Pain Ross Hauser, M.D.

Peripheral Joints & Prolotherapy Jay W. Nielsen, M.D.
Orthopedic Medicine: A Non-Surgical Approach to Chronic Pain Lawrence Cohen, M.D.

The Difference Between Prolotherapy, Trigger Points, and Acupuncture Marc Darrow, M.D.J.D.
Prolotherapy: Creating Inflammation in an Area that is Already Inflamed Marc Darrow, M.D.J.D.
Growth Factor Basis of Prolotherapy David Harris, M.D.
What Does It Take To Heal Connective Tissue? Dave Harris, M.D. 









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